Gained recognition through appearing on the E! reality TV series Keeping Up with the Kardashians alongside her famous family. She has worked as a brand ambassador for Seventeen magazine and as a runway model for Forever 21's Hello Kitty line. In 2014, she founded her own Kylie Cosmetics line and earned $420 million in sales within 18 months. After Keeping Up with the Kardashians ended in 2021, she starred on Hulu's The Kardashians.
She was a cheerleader for Sierra Canyon School, and her first modeling job was for a Sears clothing campaign titled Crush Your Style.
In August 2017, E! began airing a TV series called Life of Kylie which features Kylie's professional and personal life. In November of 2020 when Snapchat first allowed celebrities to publish their subscriber counts on their profile, she had over 35 million subscribers.